Adeno-associated virus (AAV) is a small (20 nm in diameters) replication-defective, nonenveloped virus, which infects humans and some other primate species. AAV is not currently known to cause disease and consequently the virus causes a very mild immune response. AAV can infect both dividing and non-dividing cells and may incorporate its genome into that of the host cell.
Our AAV cis vector collections offer great flexibility for choosing a specific promoter and reporter.
With our proprietary genetically engineered AAV·HT™ packaging cell and a modified rAAV cis vector, the rAAV yield is easy to reach super high level--------total 1E+15 VG. For super high level rAAV production up to 1E+15 VG total , please contact us to request a quote.
* Final viral yield may depend on the nature of transgene. For rAAV serotype 2, we guarantee final deliverable of 1.0 ml at >1E+12 VG/ml. ** Some terms may apply for custom double stranded or self-complementary rAAV production.
Features:
– Nonpathogenic with least immune response and best suitable for in vivo application.
– Excellent gene delivery efficiency in most cell types including dividing and non-dividing or primary cells.
– Integration into chromosome 19 of host genome (for wild type AAV ONLY).
– Multiple serotypes (AAV1, AAV2, AAV5, AAV6, AAV8, AAV9).
Wide Choice of AAV cis Vectors:
Service Description:
– Cloning your gene of interest (GOI) into AAV cis vector.
– La...
Features:
– Nonpathogenic with least immune response.
– Excellent gene delivery efficiency in most cell types including dividing and non-dividing or primary cells.
– Integration into chromosome 19 of host genome.
– Multiple serotypes (AAV1, AAV2, AAV5, AAV6, AAV8, AAV9).
Wide Choice of AAV cis Vectors:
Service Description:
– Cloning your gene of interest (GOI) into AAV cis vector.
– Large-scale preparation of pAAV cis plasmid.
– Medium scale tra...
Features:
– Nonpathogenic with least immune response.
– Excellent gene delivery efficiency in most cell types including dividing and non-dividing or primary cells.
– Integration into chromosome 19 of host genome.
– Multiple serotypes (AAV1, AAV2, AAV5, AAV6, AAV8, AAV9).
Wide Choice of AAV cis Vectors:
Service Description:
– Cloning your gene of interest (GOI) into AAV cis vector.
– Pilot scale transfection of AAV·HT™ 293 cells into 10×150 mm pla...
Features:
– Nonpathogenic with least immune response and best suitable for in vivo application.
– Excellent gene delivery efficiency in most cell types including dividing and non-dividing or primary cells.
– Integration into chromosome 19 of host genome.
– Multiple serotypes (AAV1, AAV2, AAV5, AAV6, AAV8, AAV9).
– Wide choice of AAV cis vectors (promoterless, CMV, CAG (also known as CBA), U6, H1, UBC, Synapsin promoters with or without reporter genes like GFP, mR...
Features:
– Nonpathogenic with least immune response.
– Excellent gene delivery efficiency in most cell types including dividing and non-dividing or primary cells.
– Integration into chromosome 19 of host genome.
– Multiple serotypes (AAV1, AAV2, AAV5, AAV6, AAV8, AAV9).
– Wide choice of AAV cis vectors (promoterless, CMV, CAG (also known as CBA), U6, H1, UBC, Synapsin promoters with or without reporter genes like GFP, mRFP, Luc, LacZ, etc).
Service Description...
