Features:
– Excellent gene delivery efficiency in most cell types including dividing and non-dividing or primary cells.
– Multiple serotypes (AAV1, AAV2, AAV5, AAV6, AAV8, AAV9).
– Integration into chromosome 19 of host genome.
– Induce efficient gene silencing.
– Wide choice of AAV cis vectors (promoterless, CMV, CAG (also known as CBA), U6, H1, UBC, Synapsin promoters with or without reporter genes like GFP, mRFP, Luc, LacZ, etc).
Service Description:
– ...
Features:
– Excellent gene delivery efficiency in most cell types including dividing and non-dividing or primary cells.
– Multiple serotypes (AAV1, AAV2, AAV5, AAV6, AAV8, AAV9).
– Integration into chromosome 19 of host genome.
– Induce efficient gene silencing.
– Wide choice of AAV cis vectors (promoterless, CMV, CAG (also known as CBA), U6, H1, UBC, Synapsin promoters with or without reporter genes like GFP, mRFP, Luc, LacZ, etc).
Service Description:
– ...
Cell-based shRNA Validation Service:
– Cloning cDNA of your targeted gene into a validation plasmid
– Design and synthesize ~6 shRNA oligoes followed by cloning them to a rAAV cis vector.
– Transient co-transfection cDNA/shRNA plasmids.
– Quantification of target gene silencing via qRT-PCR
Available shRNA Validation Platforms:
– Constitutive shRNA knockdown
– Inducible shRNA knockdown
Guaranteed Knockdown:
We guarantee the knockdown of >80% at mRNA leve...